Kunezinhlobo eziningi zokudla, uchungechunge olude lokuhlinzeka, nobunzima ekugadweni kokuphepha. Ubuchwepheshe bokubona buyindlela ebalulekile yokuqinisekisa ukuphepha kokudla. Kodwa-ke, ubuchwepheshe obukhona bokubona bubhekene nenselelo ekutholweni kokuphepha kokudla, njengokungacaci kahle kwezinto ezibalulekile, isikhathi eside sesampula sokwelashwa, ukusebenza kahle kokucebisa okuphansi, nokukhethwa okuphansi kwezingxenye eziwumgogodla zokutholwa njengemithombo ye-ion spectrometry, ephumela ekuhlaziyweni kwesikhathi sangempela kwamasampuli okudla. Libhekene nezinselele, ithimba lethu lochwepheshe eliyinhloko eliholwa u-Zhang Feng lizuze uchungechunge lwempumelelo yezobuchwepheshe ocwaningweni lwezinto ezibalulekile, izakhi eziyinhloko, nezindlela ezintsha zokuhlola ukuphepha kokudla.
Mayelana nocwaningo nokuthuthukiswa kwezinto ezibalulekile, ithimba lihlole indlela ethile yokukhangisa yezinto zokwelashwa kwangaphambili ezintweni eziyingozi ekudleni, futhi lenza uchungechunge lwezinto ezicacile kakhulu ze-adsorption micro nano structure pre-treatment. Ukutholwa kwezinto eziqondiwe emazingeni okulandelela/ukulandelela okungaphezulu kudinga ukwelashwa kwangaphambili ukuze kuthuthukiswe futhi kuhlanzwe, kodwa izinto ezikhona zinamandla alinganiselwe wokucebisa kanye nokucaciswa okwanele, okuholela ekutholeni ukuzwela okungafinyeleli izidingo zokutholwa. Kusukela esakhiweni samangqamuzana, ithimba lihlaziye indlela ethile yokukhangisa yezinto zokwelashwa kwangaphambili ezintweni eziyingozi ekudleni, lethula amaqembu asebenzayo njenge-urea, futhi lalungisa uchungechunge lwezinto ezisebenzayo zohlaka lwe-organic olunomthetho webhondi yamakhemikhali (Fe3O4@ETTA-PPDI Fe3O4@TAPB-BTT kanye ne-Fe3OPPDI4 endaweni kazibuthe ku-naparticles ye-Fe3O4@naparticles). Isetshenziselwa ukucebisa nokuhlanza izinto eziyingozi njenge-aflatoxins, izidakamizwa zezilwane ze-fluoroquinolone, nama-phenylurea herbicides ekudleni, isikhathi sangaphambi kokwelashwa sifinyezwa kusukela emahoreni ambalwa kuya emizuzwini embalwa. Uma kuqhathaniswa nezindlela ezijwayelekile zikazwelonke, ukuzwela kokutholwa kwenyuka izikhathi ezingaphezu kwekhulu, kudlula ubunzima bezobuchwepheshe bokucaciswa kwezinto ezingezinhle okuholela ezinqubweni ezinzima zokwelashwa kwangaphambili kanye nokuzwela okuphansi kokutholwa, okunzima ukuhlangabezana nezidingo zokutholwa.
Esiqondisweni socwaningo nentuthuko yezingxenye eziyinhloko, ithimba lizohlukanisa izinto ezintsha futhi lizihlanganise nemithombo ye-ion ye-mass spectrometry ukuze kuthuthukiswe izingxenye zomthombo we-ion mass spectrometry ion kanye nezindlela zokuthola ngokushesha ze-mass spectrometry yesikhathi sangempela. Njengamanje, imicu yokuhlola yegolide ye-colloidal evame ukusetshenziswa yokuhlolwa ngokushesha esizeni mincane futhi iyaphatheka, kodwa ukunemba kwayo kwekhwalithi nobuningi kuphansi kakhulu. I-mass spectrometry inenzuzo yokunemba okuphezulu, kodwa okokusebenza kukhulu futhi kudinga isampula ende yokwelashwa nezinqubo zokuhlukaniswa kwe-chromatographic, okwenza kube nzima ukusetshenziselwa ukutholwa ngokushesha esizeni. Ithimba liphule ibhodlela lemithombo ye-ion ye-mass spectrometry yesikhathi sangempela enomsebenzi we-ionization kuphela, futhi lethule uchungechunge lobuchwepheshe bokuguqulwa kwezinto ezibonakalayo ngokuhlukanisa emithonjeni ye-ion ye-spectrometry, okuvumela imithombo ye-ion ibe nomsebenzi wokuhlukanisa. Ingahlanza amasampula amasampula ayinkimbinkimbi njengokudla ngenkathi i-ionizing izinto eziqondiwe, isuse ukuhlukaniswa okunzima kwe-chromatographic ngaphambi kokuhlaziywa kwe-spectrometry mass mass, futhi ithuthukise uchungechunge lokuhlukanisa imithombo ye-ionization ehlanganisiwe yesikhathi sangempela ye-mass spectrometry ion. Uma okokusebenza okuphrintiwe kwe-molecularly kuhlanganiswe ne-conductive substrate ukuze kwakhiwe umthombo omusha we-ion we-mass spectrometry (njengoba kuboniswe kuMdwebo 2), indlela yokubona ngokushesha ye-mass spectrometry yesikhathi sangempela isungulwa ukuze kutholwe ama-ester e-carbamate ekudleni, ngesivinini sokutholwa esingu-≤ 40 amasekhondi kanye nomkhawulo wobuningi bendlela yokutholwa efika ku-μ yezinga elilinganiselwe le-g/5 elilinganiselwe kuzwelonke. kuncishiswe kusuka emashumini emizuzu kuya emashumini amasekhondi, futhi ukuzwela kuye kwathuthukiswa izikhathi ezicishe zibe ngu-20, kuxazululwe inkinga yezobuchwepheshe yokunemba okwanele kubuchwepheshe bokuthola ukuphepha kokudla esizeni.
Ngo-2023, ithimba lazuza uchungechunge lwempumelelo kubuchwepheshe obusha bokuhlola ukuphepha kokudla, ukwakha izinto ezintsha eziyisi-8 zokuhlanza nokucebisa kanye nezinto ezi-3 ezintsha zomthombo we-ion spectrometry; Faka isicelo samalungelo obunikazi ayi-15; Amalungelo obunikazi agunyaziwe ayi-14; Ithole amalungelo okushicilela ama-software angu-2; Yakha amazinga okuphepha kokudla ayi-9 futhi yashicilela izindatshana ezingama-21 kumajenali asekhaya nawangaphandle, okuhlanganisa nama-athikili angu-8 e-SCI Zone 1 TOP.